eLife6h
Range geographies, not functional traits, explain convergent range and phenology shifts under climate change
This article presents valuable findings on the impact of climate change on odonates, integrating phenological and range shifts to broaden our understanding of biodiversity change. The study leverages ...
eLife7h
Vole Parenting: A fine line between attack and care
Oxytocin neuron projections from two brain regions involved in parental care regulate both parental care and infanticidal behaviors in virgin mandarin voles.
eLife9h
Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction
Live imaging at single-vesicle resolution reveals rabphilin-3A as the first identified negative regulator of neuropeptide release in mammalian neurons.
eLife1d
Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism
Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences; Peking University International Cancer Institute; and State Key Laboratory ...
eLife1d
Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, ...
eLife1d
Arthropods dominate plant litter decomposition in drylands
An analysis of leaf litter breakdown in climatically diverse habitats shows that decomposition by larger invertebrates ...
eLife1d
Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer
The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...
eLife1d
HIV integrase compacts viral DNA into biphasic condensates
Soft Condensed Matter and Biophysics, Department of Physics and Debye Institute, Utrecht University, Utrecht, The Netherlands ...
eLife2d
A host enzyme reduces non-alcoholic fatty liver disease by inactivating intestinal lipopolysaccharide
The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...
eLife1d
Discovering Root Causal Genes with High Throughput Perturbations
We now introduce an algorithm called Root Causal Strength using Perturbations (RCSP) that discovers the surrogate ancestors of each variable using Perturb-seq and then computes the RCS of each ...
eLife2d
Maternal behavior influences vocal practice and learning processes in the greater sac-winged bat
Smithsonian Tropical Research Institute, Luis Clement Avenue, Bldg. 401 Tupper, Balboa Ancon, Republic of Panama ...
eLife2d
The Smc5/6 complex counteracts R-loop formation at highly transcribed genes in cooperation with RNase H2
The R-loop is a common transcriptional by-product that consists of an RNA-DNA duplex joined to a displaced strand of genomic DNA. While the effects of R-loops on health and disease are well ...