Mahomes' record is 10-3 straight-up and 11-1-1 against the spread when he's starting and the Chiefs are underdogs.

Of course the 49ers want another shot at the Kansas City Chiefs, a replay of the Super Bowl in Las Vegas on what turned into ...

Preparation to face the Chiefs Sunday for the 49ers included film review of last season’s 25-22 overtime loss in Super Bowl ...

Kyle Shanahan still plans to take Patrick Mahomes seriously in the 49ers' Week 7 showdown. Is Patrick Mahomes having a down ...

The latest NFL rumors involve a new Chiefs trade target, a potential Vikings upgrade, and the Raiders' outlook post-Davante Adams.

Aside from outplaying the Chiefs quarterback, the 49ers third-year signal-caller has been radically different from a ...

The 49ers look to break a four-game losing streak against the Kansas City Chiefs since coach Kyle Shanahan took over as head ...

Eight months later, the pain of losing a second Super Bowl in five seasons to the Kansas City Chiefs has barely subsided for the San Francisco 49ers as they prepare for a rare regular season rematch.

Kansas City Chiefs quarterback Patrick Mahomes' statistics this season haven't quite matched the expectations fans have for ...

Chargers Quarterback Justin Herbert meets with the media to recap the victory over the Denver Broncos, what he sees from the ...

The back-to-back Super Bowl MVP feels good about his pass-catching group despite a rocky statistical start to 2024 ...

San Francisco linebacker Fred Warner discussed the game during Tuesday's edition of "Murph and Marcus" on KNBR 680, ...