Here, different cyclin–cdk complexes cooperate with other mitotic regulators (such as Polo- and Aurora kinases) to coordinate the architectural changes in the cell. A focused presentation and ...

An enzyme called cyclin-dependent kinase 2 (CDK2) regulates the cell cycle and may have the potential to drive therapeutic ...

Cip/Kip proteins that inhibit cyclin-dependent kinase 2 (Cdk2 ... Since the 'pre-replicative complex' of ORC, Cdc6, RLF-B/Cdt1 and Mcm2-7 are involved in recruiting both Xic1 (through Cdc6 ...

Tyk Medicines Inc. has patented new cyclin-dependent kinase 2 (CDK2) and/or cyclin-dependent kinase 4 (CDK4) inhibitors reported to be useful for the treatment of cancer, infections, metabolic ...