Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.

Anti-ACE2 pAb was used as a positive control. A stable clone of ACE2-overexpressing HEK293 (HEK293-ACE2) was generated by transfection with a pcDNA3.1 plasmid which was inserted tag free native ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...