Why do women have more trouble after knee injuries? Model explains estrogen's role
A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds ...
eLife18d
How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective
This is a valuable report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...
Frontiers1mon
Fibroblasts in rheumatoid arthritis: novel roles in joint inflammation and beyond
Fibroblasts have been in the forefront of research for several ... The lung is an important non-synovial component of RA both from a clinical and an immunopathogenic aspect. Interstitial lung disease ...
C&EN1mon
Biomimetic Topological Micropattern Arrays Regulate the Heterogeneity of Cellular Fates in Lung Fibroblasts between Fibrosis and Invasion
Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...
Frontiers5y
Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D
Migration medium with or without 20% cell-free synovial fluid, 150 ng/ml CCL2, 1,000 ng/ml CCL20 or 150 ng/ml CXCL10 (all R&D Systems, Minneapolis, MN, USA) was added to the lower chamber. Each ...