Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided significantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving ...

Lupus involves unpredictable symptom flares and potential changes in brain chemistry that may increase your risk of experiencing depression and anxiety. Lupus is a chronic (long-term) autoimmune ...

Atherosclerosis cardiovascular disease (ASCVD)-related mortality is higher in patients with lupus nephritis (LN) compared ...

July 10, 2024 — Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect ...

Objectives Ethnicity and health outcomes are intrinsically interrelated, although mechanisms are complex. SLE is a disease ...

Among the total systemic sclerosis cohort, 14% of individuals were categorized as frail and 53% as prefrail, with frailty status linked to an increased risk for mortality.

Updated specific recommendations are also provided for cutaneous, neuropsychiatric and haematological disease, SLE-associated antiphospholipid syndrome, kidney protection, as well as preventative ...

Objective At least half of patients with systemic lupus erythematosus (SLE) develop organ damage as ... that were not captured by the electronic database search. Inclusion criteria included ...

Robust nomenclature reduces diagnostic delay. However, key aspects of current nomenclature are widely perceived to be out of date, these include disease definitions, classification and diagnostic ...