Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for ...

Several studies have identified RNA-splicing neojunctions in cancers such ... Further investigation will be needed to understand the mechanism that underlies how simple increases or decreases ...

Splicing is a basic requirement for producing ... they are first copied into precursors of mRNA, or messenger RNA. The spliceosome then converts them into mature, functional mRNA.

Taiwanese scientists have discovered a new way to synthesize circular RNA (circRNA), which could be applied to vaccine ...

Spliceosomes are large and dynamic RNA-protein complexes ... new insights into the mechanism of minor intron recognition and sheds light on the evolution of the splicing machinery.

Strong evidence for ALS often comes from familial forms of the disease, where specific gene mutations— for example in the ...

PepGen Inc. (Nasdaq: PEPG), a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies with the goal of transfo ...

A clinical research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and international genetic researchers led a global research study using multi-omics analysis and ...

CUGexp RNA forms based-paired structures that bind ... to identify previously unknown roles for coordinated alternative splicing and additional post-transcriptional regulatory mechanisms during ...

A clinical research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and international genetic researchers led a global research study using multi-omics analysis and ...