Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane ...
The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...
The authors’ structure unambiguously places UM171 in the company of a limited number of other molecular glue degraders, including anticancer compounds called aryl sulfonamides and ...
Chemists identify a single molecule that naturally tiles in nonrepeating patterns, which could help build materials with novel electronic properties.
Rare and powerful compounds, known as keystone molecules, can build a web of invisible interactions among species.
3d
News Medical on MSNDetailed enzyme structure offers path to targeted breast cancer drugsCancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells ...
Three years later, FDA expanded the label to include the broader treatment of primary hyperlipidemia with bempedoic acid alone or in combination with ezetimibe 3, another nonstatin and a previous ...
Mar. 5, 2025 — Some bacteria deploy tiny spearguns to retaliate against rival attacks. Researchers mimicked attacks by poking bacteria with an ultra-sharp tip. ... Mar. 4, 2025 — A vivid new ...
SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.
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