Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Chemists identify a single molecule that naturally tiles in nonrepeating patterns, which could help build materials with novel electronic properties.

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells ...

Rare and powerful compounds, known as keystone molecules, can build a web of invisible interactions among species.

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

It seeks to explain biological function in terms of molecular structure, dynamics and organization, from single molecules to supramolecular structures. HIV-1 TAR RNA plays key roles in viral ...

Scientists at Sanford Burnham Prebys and the Mayo Clinic used cryogenic electron microscopy to create 3D images detailing the overall structure of ubiquitous mitochondrial creatine kinase.

Details are provided in the text. From an energetic point of view, glycolysis is not efficient; providing only two ATP molecules per glucose molecule used. Therefore, the end glycolytic intermediate, ...

It is now clear that cancer cells can succumb to some anticancer therapies by undergoing a peculiar form of cell death that is characterized by an increased immunogenic potential, owing to the ...

Mar. 6, 2025 — A new technique builds inorganic and polymer battery electrolytes at the same time, in the same vessel. This 'one-pot' in-situ method creates a controlled, homogeneous blend ...