Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

2017; Figure 1). This review focuses on the involvement of neuroglia in neuroinflammation, exploring how glial Cxs contribute to the pathophysiology and progression of AD, PD, MS, and HD and exploring ...

However, these receptors are also present at neuroglia (astrocytes, oligodendrocytes) although at a considerably lower density. They mediate necrosis/apoptosis by the release of pro-inflammatory ...