The New England Journal of Medicine (NEJM) is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It describes itself as the oldest continuously ...

At the New England Journal of Medicine (NEJM), our mission is to publish the best research and information at the intersection of biomedical science and clinical practice. Our highly selective ...

A data sharing statement provided by the authors is available with the full text of this article at NEJM.org. Supported by three consecutive project grants (12/147, 16/078, and 20/140) from the ...