Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Mitochondria play a crucial role in cellular energy production, and their dysfunction has long been linked to metabolic ...

The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

especially as cell models become more complex and three dimensional. One way to do this is by tracking cellular metabolism, which provides information about cell activation, differentiation and ...

In this infographic, we compare two methods for tracking cellular metabolism – periodic sampling and continuous monitoring – before highlighting when continuous monitoring can benefit your research ...

Expert Rev Anticancer Ther. 2009;9(4):511-523. As the name implies, mTOR is inhibited by rapamycin. Rapamycin (also known as Sirolimus or Rapamune ®) is a macrocyclic lactone antibiotic that was ...

The Hippo-YAP1/TAZ pathway is also found to regulate metabolic disorders. Moreover, the Hippo-YAP1/TAZ pathway is involved in the regulation of senescence and ferroptosis, inflammation, and fibrosis ...

Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an 710032, ...

A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).The findings of the study are published in Science Advances.