Researchers found that newborn immune cells regenerate heart tissue by producing thromboxane. Mimicking this process in ...

Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Adipocytes in the skin contain one large liquid droplet of fat molecules (or lipids), which can be released from the cell in response to various biological events. In the two mouse models of skin ...

Metabolic disorders such as iron overload, glycolysis, insulin resistance, lipid dysregulation, and glutaminolysis are found to induce liver senescence and ferroptosis, which are hot topics in the ...

revealed that adropin regulates the macrophage lipid metabolism via PPARγ, thereby promoting the repolarization of macrophages from M1 to M2 (64). 6.4 MPO-ANCA-related lung injury Myeloperoxidase (MPO ...

As a result, oxidized LDL is continuously taken up via these receptors, loading the macrophages with cholesterol. The lipid-engorged macrophages have a foamy appearance and are called 'foam cells ...

In this important study, the authors investigate the role of mycobacterial Wag31 in lipid and peptidoglycan biosynthesis. A detailed analysis of Wag31 domain architecture revealed a role in membrane ...