Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult macrophages.

This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Adipocytes in the skin contain one large liquid droplet of fat molecules (or lipids), which can be released from the cell in response to various biological events. In the two mouse models of skin ...

Schwingshackl L, Bogensberger B, Benčič A, Knüppel S, Boeing H4, Hoffmann G3. Effects of oils and solid fats on blood lipids: a systematic review and network meta-analysis. J Lipid Res. 2018 Sep;59(9) ...

In this important study, the authors investigate the role of mycobacterial Wag31 in lipid and peptidoglycan biosynthesis. A detailed analysis of Wag31 domain architecture revealed a role in membrane ...

A speaker highlighted key advances in lipid treatment in 2024. Topics included triglyceride and lipoprotein(a) management as well as another setback to the “HDL hypothesis.” In 2024 ...

Lipid abnormalities play a critical role in ... LDL particles in excess infiltrate the artery and are retained in the intima. Macrophage uptake of modified LDL particles leads to cell accumulation ...

Division of Physiological Chemistry and Metabolism, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan Laboratory of Metabolomics, RIKEN Center for Integrative ...