This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult ...

Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-dependent nuclear receptor that has a critical role in adipogenesis, glucose metabolism and placental function 1,2,3. This ...

A speaker highlighted key advances in lipid treatment in 2024. Topics included triglyceride and lipoprotein(a) management as well as another setback to the “HDL hypothesis.” In 2024 ...

Adipocytes in the skin contain one large liquid droplet of fat molecules (or lipids), which can be released from the cell in response to various biological events. In the two mouse models of skin ...

As a result, oxidized LDL is continuously taken up via these receptors, loading the macrophages with cholesterol. The lipid-engorged macrophages have a foamy appearance and are called 'foam cells ...

Lipid nanoparticles (LNPs) represent a highly promising nonviral delivery platform for a variety of therapeutic nucleic acids, including short interfering RNA (siRNA), mRNA (mRNA), single-guide RNA ...

There is currently no research that supports the alleged health benefits of the so-called "carnivore diet," which consists entirely of meat and animal products. In fact, most nutritionists will ...