A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the ...

Researchers at the Harvard Medical School discovered that the enzyme GUK1 promotes lung cancer growth by boosting the ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

2023). The key breakthrough in the quest for selective SIRT2 inhibitors resides in screening inhibitors that target specific structural domains distinguishing SIRT2 from other proteins within the ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality. Targeting oncogenes ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These molecules do more than fuel the body—they directly influence gene expression and ...