Our findings suggest a novel dual role for IFT172 in both structural support within IFT trains and regulation of ciliary ubiquitination and signaling pathways, providing new insights into the ...

What is Zollinger-Ellison syndrome? Zollinger-Ellison syndrome (ZES) is a rare digestive disorder. If you have ZES, you likely have 1 or more tumors in the first part of the small intestine, the ...

Cilia are important for regulating cellular processes, but because of their small size and number, it has been difficult for scientists to explore cilia in brain cells with traditional techniques ...

Taken together, the results of the present studies of iPSCs derived from an LS patient and the IOB mouse model of LS show that mitochondrial activities, mtDNA loss and ciliary homeostasis are involved ...

Cellular organelles are rarely considered as biomarkers. Our work on a tiny hair-like organelle called cilia found in most cells and the proteins inside them as potential biomarkers that inform ...

Cuboid syndrome is a condition caused by an injury to the joint and ligaments surrounding the cuboid bone. The cuboid bone is one of the seven tarsal bones in the foot. Cuboid syndrome causes pain ...