Cilia are outgrowths of the plasma membrane of eukaryotic cells that contain a specialised cytoskeleton. Motile cilia are present on multiciliated cells and use this cytoskeleton to move fluid ...

Asperger's syndrome refers to a high-functioning form of autism. Although it was once classified as its own condition, Asperger’s is no longer an official diagnosis in the Diagnostic and ...

Background: Among patients with autism spectrum disorders (ASD) evaluated in our clinic, there appears to be a subset that can be clinically distinguished from other ASD children because of ...

Primary ciliary dyskinesia, formerly known as immobile cilia syndrome, is caused by defects in the structure and function of cilia. Chronic sinusitis, otitis media, infertility, inverted position, and ...

The HSVM investigations showed slow-moving cilia beat frequency at 6.5 Hz. A total of 98% of the cilia showed normal beating, while 2% were immotile cilia. There was no obvious stiffness at the base ...

Metabolic syndrome is a constellation of conditions that together increase the risk of type 2 diabetes, stroke, and cardiovascular problems, including heart attack. The features of metabolic syndrome ...

Our findings suggest a novel dual role for IFT172 in both structural support within IFT trains and regulation of ciliary ubiquitination and signaling pathways, providing new insights into the ...

med.unipi.it Background In primary ciliary dyskinesia (PCD) lung damage is usually evaluated by high-resolution CT (HRCT). Objective To evaluate whether HRCT abnormalities and Pseudomonas aeruginosa ...

1 Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK Background Quality of life (QOL)-primary ciliary dyskinesia (PCD) is the first ...

2020). However, how defects in XAP5 lead to XLID syndrome is unknown. Although there is as yet no evidence that XAP5 regulates ciliogenesis in any system besides Chlamydomonas and mice, the function ...