This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

Histone modification can open chromatin ... Likewise, demethylated DNA does not draw deacetylating enzymes to the histones, but it often attracts histone acetyltransferases, allowing histones ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Epigenetic modifiers, enzymes that catalyze covalent modifications on chromatin ... into the catalytic and noncatalytic functions of the histone methyltransferase SETD2, a protein responsible ...

The SCAN enzyme is at the heart of this discovery ... in metabolic and signaling functions, including histone acetylation and protein modification. However, its role in NO transport via SNO ...

Sir2 is not an ADP-ribosylating enzyme--an enzyme that adds ADP ribose to a protein, as some studies had suggested and which they had been trying to prove--but rather, it is a histone deacetylase, an ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging process may be more resilient than previously thought, according to a new study ...

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site of modifications, chemical additions referred to as epigenetic marks ...