This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

Histone modification can open chromatin ... Likewise, demethylated DNA does not draw deacetylating enzymes to the histones, but it often attracts histone acetyltransferases, allowing histones ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...

The SCAN enzyme is at the heart of this discovery ... in metabolic and signaling functions, including histone acetylation and protein modification. However, its role in NO transport via SNO ...

In addition, we discuss how these histone modifications not only lead to pathogenesis ... through the recruitment of histone-modifying enzymes Histones are hypoacetylated in mouse models of ...

Indeed, the enzyme “was most similar to bacterial restriction modification enzymes ... Yushenova further demonstrated that bdelloids possess a histone methyltransferase that preferentially recognizes ...

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site of modifications, chemical additions referred to as epigenetic marks ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

Sir2 is not an ADP-ribosylating enzyme--an enzyme that adds ADP ribose to a protein, as some studies had suggested and which they had been trying to prove--but rather, it is a histone deacetylase, an ...

Epigenetic modifiers, enzymes that catalyze covalent modifications on chromatin ... into the catalytic and noncatalytic functions of the histone methyltransferase SETD2, a protein responsible ...