Not all scars are created equal. That's the conclusion of a new study by Weizmann Institute of Science researchers: They found that two distinct types of scars, referred to as "hot" and "cold," can ...

Cells in living tissues are constantly exposed to changes. And although many conditions can be replicated in the lab with ...

A new molecular imaging technique— 18 F-FAPI PET—can detect the first signs of tissue ... heart and pulmonary artery of patients decreased, suggesting the potential reversibility of fibroblast ...

F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach ...

Study Identifies Subtypes of Fibroblasts in Skin Cancer Nov. 19 ... Gene Signatures from Tissue-Resident T Cells as a Predictive Tool for Melanoma Patients May 2, 2024 — A new study has revealed ...

Because fibroblasts are known to be involved in PAH-related tissue remodeling, the team of researchers tested ... Wang noted that, “after PAH-targeted therapy, the uptake of 18F-FAPI in the right ...

This phenomenon includes not only the replacement of the damaged tissue by a fibrotic scar produced ... in orchestrating the transdifferentiation of fibroblasts and ensuing fibrotic remodeling of the ...

The findings revealed an increased presence and co-localization of cytotoxic T cells, conventional dendritic cells, and inflammatory fibroblasts in myocarditis-affected heart tissue. Meanwhile, blood ...

Using human myocardial samples, the degree of tissue hypoxia ... in cardiac fibroblasts during prolonged hypoxia which may contribute to the pro-fibrotic nature of an ischaemic event. Targeting ...