The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

The dominant rationale to generate new (and to assess old) anticancer chemotherapeutic agents is to determine their cell-autonomous effects — that is, their capacity to reduce the growth ...

This study aims to analyze the distribution characteristics of IgG4-expressing cells, regulatory T cells (Tregs), and M2-type macrophages as well as to elucidate the relationship between IgG4 and the ...

Moreover, a dual CCR2/CCR5 antagonist reduced macrophage-mediated inflammation and prevented IR, providing a therapeutic potential for metabolic diseases linked to obesity. Another promising strategy ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

State Key Laboratory of Optical Fiber and Cable Manufacture Technology, Yangtze Optical Fibre and Cable Joint Stock Limited Company; Optics Valley Laboratory, Wuhan, Hubei 430073, China ...