Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk ...

Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Department of Biomaterials and Biomedical Technology, The Personalized Medicine Research Institute (PRECISION), University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 ...

Treatment of monocytes and macrophages with high concentrations ... target for the development of anti-inflammatory drugs. Figure 1: PPAR-γ–deficient ES cells can differentiate into macrophages.

Human monocytes and liver-derived macrophages were phenotypically characterised using ... unless otherwise specified in figure legends.

1 Department of Radiation Oncology, The First Medical Center of Chinese PLA General Hospital, Beijing, China 2 Department of Radiation Oncology, General Hospital of Southern Theatre Command of PLA, ...

With the world figure skating championships in Boston at the end of March, the Americans are hoping to use their home ice advantage to find some spots on the podium. The U.S. worlds team was ...