Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Treatment of monocytes and macrophages with high concentrations ... target for the development of anti-inflammatory drugs. Figure 1: PPAR-γ–deficient ES cells can differentiate into macrophages.

Monocyte-like macrophage (MLM) accumulation precedes colitis-associated ... adjacent tissues in mice 6 or 9 weeks after AOM-DSS induction (online supplemental figure 3E-J, 4A-F). Indeed, an increase ...

Figure 1 The niche of macrophages in bone tissues ... can also be selectively activated according to the degree of inflammation, while monocyte-derived pro-inflammatory macrophages occupy available ...

Beyond their established roles in maintaining normal heart function, both resident and monocyte-derived macrophages ... impact cardiac and pericardial macrophage subsets and functions. CI wrote, ...

Human monocytes and liver-derived macrophages were phenotypically characterised using ... unless otherwise specified in figure legends.

The enzyme aconitate decarboxylase 1 (Acod1) is known to link the cellular function of monocyte-derived macrophages to their metabolic status ... can be found in the figure legends. P values less than ...

Monocytes were differentiated into macrophages for 7–10 days in differentiation media ... Monozygotic twins were identified with JIA (figure 1A). Both sisters were diagnosed with oligoarticular JIA at ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...