Hosted on MSN1mon
Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes
Their method relies on combining fibroblast growth factor 4 (FGF4 ... Their results revealed key improvements: better cell structure with well-defined sarcomeres and T-tubules, enhanced electrical ...
Nature19d
The FGF family: biology, pathophysiology and therapy
Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...
Nature1mon
Semirational design of a potent, artificial agonist of fibroblast growth factor receptors
Fibroblast growth factors (FGFs) are being investigated in human clinical trials as treatments for angina, claudication, and stroke. We designed a molecule structurally unrelated to all FGFs ...