Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

The lack of tissue regeneration is attributed to an overall absence of axon-growth promoting factors (eg, the local presentation of growth promoting factors and extracellular matrix (ECM ...

Bioscaffolds derived from the extracellular matrix ... and the cell-adhesive glycoproteins laminin and fibronectin. Next, novel 2-D coatings were generated using the DNP or commercially-sourced bovine ...

RT-qPCR, western blot, and immunofluorescent staining assessments showed that USH2A mutations induced apoptosis of iPSCs and ROs, and deficiency of the extracellular matrix ... ECM components such as ...

For example, extracellular β-lactamase enzymatic activity against P. aeruginosa occurs within the matrix 76 ... constituent planktonic organisms. A collagen-binding protein (Cna) and two ...

Potential mechanisms for the attachment of epithelial ovarian cancer cells to the peritoneal mesothelium include binding to extracellular matrix proteins such as collagen type I and IV, laminin, and ...

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues. However, a new study challenges that notion, revealing an unexpected confirmation in ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...