More than 50% of patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) during the disease, which may ...

July 10, 2024 — Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect ...

Attempting to obtain an accurate diagnosis is important; SLE requires treatment with immunosuppressive agents, whereas APS might require other approaches, including anticoagulation, fresh frozen ...

In response, the body prioritizes central blood volume by reducing circulation to the skin, which can result in a purple-red rash appearing on the cheeks and the bridge of the nose. Shaped ...

Hypertrophic LE is a rare subset of chronic cutaneous LE and represents 2% of the total chronic cutaneous lesions of LE. [1,2] Hypertrophic LE is similar to discoid LE but with marked ...

A 2021 review of 17 studies involving 1,326 participants (635 with lupus and 691 without) found that 27% of individuals with systemic lupus erythematosus (SLE) had hearing loss. This was ...

Adult diaper rash can develop when wearing adult diapers, incontinence briefs, or pads. It typically begins as small, inflamed patches of irritated skin and progresses to larger patches of raised ...

Systemic lupus erythematosus commonly presents as a rash. The rashes are caused by inflammation from the immune system fighting the body. Systemic lupus erythematosus, more commonly known as lupus ...

Dermatomyositis and lupus are autoimmune conditions that may share symptoms like skin rashes, muscle weakness ... lupus diagnosis (mostly cutaneous lupus erythematosus) and later developed ...

Systemic lupus erythematosus, more commonly known as lupus, has a variety of symptoms and room for improvement when it comes to treatment. Cutaneous lupus erythematosus is a common manifestation ...

A 62-year-old man with hypertension, obesity, and gout presents with a 4-day history of fever, rash, abdominal pain, and lymphadenopathy. Five weeks earlier, the patient was hospitalized for gout and ...

Cytotoxic interface dermatitis (CID) is a cutaneous immunological reaction at the dermal-epidermal junction (DEJ) (1). The mononuclear cell-rich infiltrate (usually lymphocytic) may obscure the DEJ (2 ...