How nature organizes itself, from brain cells to ecosystems
Look around, and you'll see it everywhere: the way trees form branches, the way cities divide into neighborhoods, the way the ...
Fred Hutchinson Cancer Center8d
New methods reveal cancer mechanism in ancient genes
Researchers at Fred Hutch Cancer Center have discovered an overlooked mechanism driving aggressive breast and brain tumors ...
GEN21d
Arc Institute’s AI Model Evo 2 Designs the Genetic Code Across All Domains of Life
The Evo 2 preprint described three design tasks that span different levels of genomic ... accessibility profiles to simulate eukaryotic gene regulation. When asked about plans for experimental ...
Frontiers22d
Functional annotation of eukaryotic genes from sedimentary ancient DNA
We compare four different functional gene annotation pipelines for their use in detecting functional eukaryotic genes in metagenomic shotgun sequencing from a sedaDNA dataset retrieved from Lake Lama ...
University of Oslo23d
MBV4120 – Eukaryotic Genes and Genomes
Knowledge of the content of eukaryotic genomes, such as unique and repeated sequences, mobile elements and coding- and non-coding DNA. To know the principles of different levels and types of ...
BMJ1mon
Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis
Using the same computational approach, we also identified genes that are uniquely overexpressed in different MSA-defined subtypes. These included apolipoprotein A4 (APOA4), which is only expressed in ...
eLife1mon
The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2
To identify novel regulators of cellular proliferation, we utilized a whole-genome chemogenetic approach to identify genes that sensitized or lent resistance to inhibitors of different cell cycle ...
Nature2mon
Coordination of gene expression between organellar and nuclear genomes
In sugar-starved plant mitochondria, gene regulation ... of eukaryotic cells: not only are chloroplasts and mitochondria of great bioenergetic importance, but they synthesize many different ...
ki.se1y
Regulation of Gene Expression during Viral Infection – Gerald McInerney Group
Our research concerns the study of the interactions between viruses and their host cells in the early stages of infection. Using Semliki Forest virus as a model, we are exploring the involvement of ...
University of Oslo3y
BIOS9610 – Eukaryotic Genes and Genomes
The course will concentrate on gene structure, chromatin structure and genomic complexity; different levels and categories of gene regulation and the significance of non-coding RNA. The course will ...
eLife3y
A precisely adjustable, variation-suppressed eukaryotic transcriptional controller to enable genetic discovery
1963), means to express genes conditionally to permit observation ... that prokaryotic repressors likely work through different mechanisms than mechanisms used by repressors native to eukaryotes (Wang ...