This knowledge came primarily from traditional biochemical assays, which identify the molecules that bind to DNA during repair, but cannot explain the intermediate and dynamic protein activity ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or ...

Researchers from the Huntington's Disease Center, UCL Queen Square Institute of Neurology, and UK DRI at UCL have taken major ...

"We demonstrate the same DNA mismatch repair genes that are modifiers in the ... If other striatal neuronal types or non-neuronal cells are included in this assay, the majority of repeats remains at ...

Defective DNA repair in hypoxic cells could alter the sensitivity ... it is also desirable to test the efficacy of new molecular-targeted agents under normoxic and hypoxic (both acute and chronic ...

4 Given their roles in DNA replication and repair, it is unsurprising that scientists have targeted ... and products such as the LysA™ Universal PARylation Assay Kit from BPS Biosciences gives ...

Published in Cell Reports Medicine, results of a VHIO-led study support the feasibility of using RAD51 testing to complement next-generation sequencing (NGS) for precise patient stratification and ...

Results of a study led by the Vall d'Hebron Institute of Oncology (VHIO) support the feasibility of using RAD51 testing to ...