Similarly to mice that lack other regulators of the cytoskeleton, HEM1-deficient T cells showed decreased activation and proliferation compared with wild-type T cells. Surprisingly, some T-cell ...

Since paxillin is present in all cells as a link between integrins and the cytoskeleton, it also serves as a marker to visualize the dot-like and line-like anchoring points, i.e. focal adhesions.

The Milestones are a series of specially written articles, which highlight the most influential discoveries in the field of cytoskeleton over the past 60 years. Nature Milestones in Cytoskeleton ...