Myelodysplasticsyndrome (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell diseases leading ... Both diseases lead to insufficient hematopoiesis. Chronic fatigue due to anemia, ...
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
cells expressing various checkpoints that reflect an immunosuppressive tumor microenvironment (TME). However, there remains a lack of data on the clonal evolution and differentiation pathways ...
Introduction: Clonal Hematopoiesis of Indeterminate Potential (CHIP) is characterized by the expansion of a blood-cell clone due to somatic mutation in hematopoietic stem cells, in the absence of ...
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T1 Tumor limited to the pancreas and size <2 cm T2 Tumor limited to the pancreas and size 2–4 cm T3 Tumor limited to the pancreas and size >4 cm or invading duodenum or bile duct T4 Tumor ...
NAINR. 2004;4(4):231-239. Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis, condition in which the majority of erythrocytes are ...