Lipid nanoparticle platform delivers mRNA to the brain
This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...
New research on microplastics in brains reminds us that while scientists compile safety data, our leaders should still act ...
News Medical on MSN15d
3D Model Accurately Mimics the Blood–Brain BarrierA 3D model has been developed that accurately replicates the complex structures of cerebral blood vessels, enabling researchers to mimic the blood–brain barrier.
Here, we highlight the complex molecular signaling that takes place in neurons, glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 ...
1don MSN
Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.
When military personnel fire certain powerful weapons, they are exposed to a blast wave that sends blood surging from the body to the brain. This “tsunami in the body” is one way a blast can ...
Addressing the harmful chemical processes that accompany blunt force trauma to the brain can reduce the risk of long-term ...
Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...
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