Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...

enter the cell cycle, and differentiate into new myocytes and blood vessels that significantly contribute to changes in myocardial mass during physiological or pathologic remodeling The success of ...

Regulation of IL-6 plays a crucial role in bone maintenance and remodeling. Commonly ... which feed the tumor cells and promote disease progression (17, 18). This vicious cycle leads to a poor quality ...

ACE indicates angiotensin-converting enzyme; ALK-1, activin receptor-like kinase 1; AT-II, angiotensin II; BMPR2, bone ... Krebs cycle to initiate normal mitochondrial aerobic metabolism.

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) and a common cause for neurological disabilities in young adults. Although it is known that the peripheral ...

The structural integrity of bones has been attributed to bone remodeling—a highly regulated process of bone formation and bone resorption (dissolving old and damaged bones), driven by osteoblast ...

The structural integrity of bones has been attributed to bone remodeling-aa highly regulated process of bone formation and bone resorption (dissolving old and damaged bones), driven by osteoblast ...