This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Miist Therapeutics, a physics-based developer of inhaled medicines, today announced $7M in seed funding from investors ...

When these particles reach the peripheral lung, where the blood-air barrier is 100x thinner than ... vibration to generate and deliver 2-micron aqueous drug particles to the peripheral lung ...

those with diameters below 40 nm can enter the cell nucleus and those that are smaller than 35 nm can pass through the blood–brain barrier and enter the brain. Understanding the way ...

For brain imaging, they have to be able to pass through the blood–brain barrier (a protective barrier ... coated QDs is usually 20% or lower in aqueous solutions. As a result, design strategies ...

The blood-brain barrier (BBB) is located at the interface between the vascular ... To enhance stability, MBs are filled with a high molecular weight gas with low aqueous solubility, such as ...

Doing so may prevent the vicious cycle of hypotony, blood-aqueous barrier breakdown, inflammation and oedema which gives rise to reduced aqueous production and persistent hypotony.13 Early ...

In ARC eyes, several factors can contribute to early transient IOP spike: (1) postoperative inflammation attributable to disruption of the blood–aqueous barrier (BAB); (2) deformation of the outflow ...

The challenges to developing catalase as a therapeutic agent were caused by the rapid metabolism of catalase and the penetration across blood-brain barrier (BBB ... liposomes can load drugs within the ...