Certain drugs and a host of nonpharmacologic therapies are key to treating patients who have nociplastic pain, a relatively ...

Google searches exposed me to varying implications ranging from common to extreme, like Klinefelter syndrome (in which people ...

Most B cells produced in the bone marrow have some level of autoreactivity. Despite efforts of central tolerance to eliminate these cells, many escape to periphery, where in healthy individuals, they ...

Figure 2 Network diagram of immune components represented in mechanistic models of autoimmune diseases. Green color – cytokines; yellow color – cells; red color – other components; size of a node – ...

In total, 1507 adults patients with AIIRDs who received inactivated COVID-19 vaccine participated in this study (flow diagram in online supplemental figure 1). The median age of participants was 39 ...

Autoimmunity is a process by which the immune system reacts against the body's own tissues. Chronic and/or excessive autoimmune responses can result in autoimmune diseases. In December 2024, the ...

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

Researchers identify key protein to potentially halt autoimmune diseases and allergies Date: January 21, 2025 Source: Houston Methodist Summary: Researchers identified a key protein as a potential ...