A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

In addition, androgens regulate gene expression in tissues throughout the body, including skeletal muscle, by binding to a ...

and it also blocks androgen receptors in the skin. Estrogen stimulates angiotensin synthesis and enhances aldosterone-mediated water and sodium retention, making it responsible for such unpleasant ...

Shanghai Yidi Biotechnology Co. Ltd. has synthesized proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase coupled to an androgen receptor targeting moiety via a linker reported ...

Co. Ltd. has identified proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase binding moiety coupled to an androgen receptor targeting moiety through a linker acting as androgen ...

"Importantly, when we removed the receptor protein from mice that binds to androgens, the Androgen Clock stopped. Moreover, when we gave androgen to females, the clock started ticking again.