Both homeostatic and inflammatory functions of macrophages require the precise stability of lipid-rich microdomains located at the cell membrane for the initiation of downstream signaling cascades.

8) In insect cells, but not in mammalian cells, sNS1 is secreted to the extracellular media via a nonclassical and caveolin-1-dependent pathway ... a reasonable hypothesis is that NS1 performs its ...

We have demonstrated that elevated caveolin protein levels are associated with human prostate cancer progression in pathological specimens 1. Here we show that suppression of caveolin expression ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

The liver performs hundreds of vital functions, including converting nutrients from food into energy, filtering toxins from the blood, and producing bile, a key substance in digestion and waste ...

Perturbation of dystroglycan function underlies several muscular dystrophies and is also a secondary consequence of adenocarcinoma progression. Changes to the post-translational modification of ...

1 Since the discovery in 1987 that NO was similar to endothelium derived relaxing factor (EDRF), 2 its importance in the regulation of body functions, including the respiratory tract, has become ...

The patient was thought to also be affected with a limb girdle muscular dystrophy. DNA studies for Xp21, FKRP, SMN, GNE and caveolin 3 showed no abnormality. Further genetic studies are pending. Serum ...