He recommends letting frozen grapes melt in your mouth. “The cold temperature activates TRPM8 receptors in the mouth, which ...

Peripheral or central activation of the TRPM8 (transient receptor potential melastatine family member 8) cool-sensitive ion channel can produce an analgesic effect, reversing hypersensitivity and ...

The researchers have developed an innovative molecule called azo-menthol, which is able to precisely control TRPM8 channels using light, as they report in the journal Angewandte Chemie. "With azo ...

a novel TRPM8 agonist delivered via an ophthalmic eyelid wipe, for the treatment of dry eye disease. The trial enrolled 150 patients in 10 sites in the United States (NCT06400459). Given the novel ...

Researchers at the University of Edinburgh (Scotland) set out to test whether TRPM8, a 'cool-sensitive' transient receptor potential cation channel, is involved in the pain-relief mediation of ...

A collaboration between amateur and professional astronomers has led to a major discovery about Jupiter's clouds, challenging a long-standing belief.

IVIEW Therapeutics Inc., a clinical-stage biotechnology company dedicated to advancing innovative treatments for ocular diseases, today announced positive topline data from its Phase ...