Medscape4d
FDA Approves Vimseltinib for Tenosynovial Giant Cell Tumors
The US Food and Drug Administration has approved vimseltinib (Romvimza, Deciphera Pharmaceuticals, LLC) to treat adult ...
BMJ16d
Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?
They can be found in both layers of this synovial membrane and contribute to normal joint function by producing extracellular matrix components and lubricants. However, under inflammatory conditions ...
BMJ16d
Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo
zju.edu.cn Background Osteoarthritis (OA) is a degenerative joint disease characterised by cartilage degradation and chondrocyte hypertrophy ... were transferred to a polyvinylidene difluoride ...
C&EN1mon
Ordered Interfacial Water Generated at Poly(ionic liquid) Membrane Surface Imparts Ultrafast Water Transport and Superoleophobicity
Ganjiang Innovation Academy, Chinese Academy of Sciences, Ganzhou 341000, China CAS Key Laboratory of Green Process and Engineering, State Key Laboratory of Multiphase Complex Systems, Beijing Key ...
C&EN1mon
Volatile Sieving Using Architecturally Designed Nanochannel Lamellar Membranes in Membrane Desalination
Key Laboratory of New Membrane Materials, Ministry of Industry and Information Technology, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing ...
Frontiers8mon
Advances in pharmacological effects and mechanism of action of cinnamaldehyde
The degree of myocardial hypertrophy was evaluated by pathological and molecular ... RA by inhibiting the activation of the PI3K/AKT signaling pathway in the synovial membrane. Research revealed that ...
Frontiers3y
METTL3 Promotes Activation and Inflammation of FLSs Through the NF-κB Signaling Pathway in Rheumatoid Arthritis
As a chronic inflammatory disorder, it involves synovial hypertrophy, severe joint damage ... causing abnormal inflammation in the synovial membrane (8, 9). What is more, the activated FLSs release ...