A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds ...

While it has been believed that RA-FLS are generated in the inflamed synovium through transformation or differentiation of existing synovial fibroblasts, recent interest has expanded towards the role ...

Of note, circulating and synovial levels of DcR3 are also increased in patients with RA in comparison with healthy controls, and rheumatoid arthritis fibroblast-like synoviocytes can produce high ...

Synovial fibroblasts are mesenchymal cells recognized as a key cell population in RA due to their hyperproliferative and hypersensitive properties in the inflammatory milieu and hyperproduction of ...

To test this hypothesis, we analysed the effect of FFA on synovial fibroblasts (SF), human chondrocytes and endothelial cells. We also investigated whether the toll-like receptor 4 (TLR4), which can ...

The synovial membrane consists of the intimal lining layer facing the joint cavity and the sublining layer. The intimal lining layer is home to two types of cells—macrophage-like synoviocytes (Type A ...

Welcome to the HSS synovial pathology scoring image directory. Here you will find instructions for scoring 20 histologic features of synovial frozen sections that predict whether the sample synovium ...

“It doesn’t surprise me per se, because the theory was always there.” Experiments in the 1960s had revealed that the fibroblast-containing dermal compartment of the skin determines the identity of the ...

SNMMI Procedure Standard/EANM Practice Guideline for Fibroblast Activation Protein (FAP) PET Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy ...

This is a valuable report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...