The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
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EMBL researchers reveal new structural insights into minor spliceosome function
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
Mapping the human brain's default mode network: Anatomical study suggests it has widespread influence
The default mode network (DMN) is a set of interconnected brain regions known to be most active when humans are awake but not ...
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Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...
Rewriting the Rules of Aging: New Chromatin Discovery Challenges Conventional Wisdom
The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...
Science Daily6d
Uncovering how developmental genes are held in a poised state
New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...
Repressed but ready to go: How bivalency holds developmental genes in a poised state for expression
As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...