A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

These cells coordinate bodily functions and movement quickly, often without intentional thought. They also can be affected differently by health conditions. Talk with your healthcare provider if you ...

Researchers have succeeded in creating a close connection between individual cells and organic electronics. The study lays the foundation for future treatment of neurological and other diseases with ...

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is commonly known to be responsible for protein trafficking and secretion. In ...

Jonathan R. Brestoff is in the Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. To fill this knowledge gap, Ikeda and colleagues ...

Multiple unique moonlighting functions have been reported for human GS which will be reviewed here. GS structure and function have been studied for decades but new features and functions are still ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

Both humans and trypanosomes are eukaryotic ... the cell. Unlike its human counterpart, which has two sub-units, the trypanosome nuclear cap-binding complex consists of four subunits. The function ...