AI could be useful for screening methods such as epitope/paratope mapping to predict the areas of the antibody (the paratope) and antigen (the epitope) involved in binding. However, AI methods can ...

Highly diverse molecular libraries have recently become a vital tool in the search for molecules with novel properties. The antibody molecule in particular has been the focus of extensive ...

Antibody therapies are a type of biologic. They are typically monoclonal antibodies selected to bind to a particular protein (often a cell-surface protein), and produced using recombinant DNA ...

Unit of Biophysics, Department of Biochemistry and Molecular Biology, Facultat de Medicina, Av. Can Domènech s/n, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Catalonia, Spain ...

In this manuscript, the authors describe a new AlphaFold2 pipeline called PabFold that can represent a useful tool for identifying linear antibody epitopes (B-cell epitopes) for different antigens.