Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, ...

Mitochondria located in the axon, a neuron’s output structure, are discrete organelles that are either stationary or motile. 2 In contrast, mitochondria are jammed together and often overlap in ...

Another intriguing issue that will need to be further addressed is the question of why functional mitochondria are lost in the neuronal terminals more than in the cell body. The authors propose ...

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...

View Full Profile. Learn about our Editorial Policies. The paper Q. Zhang et al., “The memory of neuronal mitochondrial stress is inherited transgenerationally via elevated mitochondrial DNA levels,” ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca 2+ signaling. In particular ...

Although concurrent inhibition of mitochondrial calcium uptake substantially enhanced this cytoplasmic calcium increase, it significantly reduced glutamate-stimulated neuronal cell death.

Scientists have discovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) that links neuronal activity to mitochondrial function. This mechanism plays a critical ...

Farris and her team discovered that mitochondria in CA2 neurons are not uniform. Instead, their structure and function vary depending on their location within the neuron. Mitochondria in the ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ ...