The name multiple sclerosis refers to scars (scleroses—better known as plaques or lesions) particularly in the white matter of the brain and spinal cord, which is mainly composed of myelin.

For instance, demyelination of nerves in the lower spine may affect leg movement ... In some chronic conditions, like multiple sclerosis (MS), demyelination progresses over years.

Multiple sclerosis, or MS, is a chronic neurological disease that impacts the brain, spinal cord, and central nervous system. Your brain uses electrical signals to communicate with your body.

More information: Aletta M. R. van den Bosch et al, Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation, Nature Communications (2024). DOI: 10.1038/s41467 ...

There’s no single test that can diagnose multiple ... active lesions often show inflammatory demyelination, while old lesions may show scarring that is often described as “sclerosis.” ...

Positive spinal cord MRI (≥ 2 focal T2 lesions); c. Positive CSF Table used with permission: National Multiple Sclerosis Society Research Bulletins. International panel updates diagnostic ...

Currently, patients with clinically isolated syndrome (CIS) and brain lesions on MRI suggestive of multiple sclerosis (MS), are offered a confirmatory MRI scan after 6 months. Researchers in Italy ...

A Phase 2 clinical trial testing obexelimab in adults with relapsing types of multiple sclerosis is now recruiting ...

Experts in Australia and New Zealand have published the first consensus guidelines for the care of adults with MS in those ...

Multiple sclerosis is a chronic and potentially debilitating ... that surrounds nerve cells in the brain and spinal cord. When this lining becomes inflamed or destroyed, it slows down and disrupts ...