This new model has led to the identification of novel therapeutic targets that could potentially block tau spread. The preclinical study , published April 5 in Cell , is a significant advancement ...

In a remarkable moment for Alzheimer’s disease research, scientists at Weill Cornell Medicine have developed an innovative human neuron model that successfully simulates the spread of tau ...

Infections, chemicals, stress—these environmental factors influence the risk of developing psychiatric or neurological ...

One gene, GSK3β, weakens neuron defenses against oxidative stress. ApoE4 astrocytes cause hyperactivity and oxidative stress in neurons. This isn’t the first 3D model system involving hiPSC-derived ...