This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

The Kostenki 11 site, located near the Don River, just 300 kilometers from Moscow, is one of the most significant Upper ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

In bacteria, there’s a risky situation where RNA can stick to its DNA template, forming a structure called an ... “At that time, we couldn’t figure out what RapA was doing,” Darst said. However, ...

Program in Chemical Biology, Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239, United States ...

A new study led by Yale University and the Broad Institute of MIT and Harvard academics has discovered that the human genome, which is missing compared to the genomes of other primates, may have been ...