Unfolded protein response: A key regulator of intestinal health and disease
The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...
ahajournals.org8h
Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA
BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.
eLife19h
Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer
These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...
eLife19h
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation
This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...