a novel methionine adenosyltransferase 2A (MAT2A)-inhibitor being explored for solid tumors. SYH2039 targets solid tumors that have a mutation called MTAP deletion, which is estimated to be ...

Caption MAT2A is an enzyme that plays an essential role in cell function and survival and the primary producer of S-adenosylmethionine (SAM), the universal methyl donor. Inhibition of MAT2A ...