The Finley Lab investigates how cellular metabolic pathways regulate cell fate decisions in stem cells and cancer cells. We combine genetic and metabolomic approaches to investigate cell-type specific ...

Cell Metabolism, launched in January 2005 ... with an emphasis on understanding the molecular basis of how the body self-regulates in the face of change, and how disturbances in these balances ...

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin. One day, researchers want to use switches of this kind ...

The cell can control a metabolic pathway by the presence or absence of a particular enzyme. The cell can also regulate the rate of reaction of key enzymes. Enzymes are able to bind to their ...

A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...

Mitochondria play a crucial role in cellular energy production, and their dysfunction has long been linked to metabolic ...

However, how birth-associated metabolic changes affect the fate of tissue stem ... Considering that glutamine metabolism also regulates the functions of tissue stem cells other than NSCs, our ...

Following digestion and absorption of dietary fat, TG and cholesterol are packaged to form chylomicrons in the epithelial cells of the intestines. Chylomicrons circulate through the intestinal ...